官网链接
折扣/货期| 货号：43002-1 mg | 规格：1 mg | 目录价：￥4409 |
| 货号：43002-10 mg | 规格：10 mg | 目录价：￥17634 |
| 货号：43002-5 mg | 规格：5 mg | 目录价：￥11028 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ARV-471
别名:
Vepdegestrant
产品描述:
A PROTAC that drives ER degradation; induces degradation of ER in MCF-7 cells (DC50 = 0.9 nM); inhibits the growth of T47D and MCF-7 cells expressing wild-type ER (GI50s = 4.5 and 3.3 nM, respectively) and T47D cells expressing ERY537S or ERD538G mutations (GI50s = 8 and 5.7 nM, respectively); reduces tumor growth in an MCF-7 orthotopic mouse xenograft model at 3, 10, and 30 mg/kg per day; induces tumor regression in a PDX ERY537S-expressing mouse model of breast cancer at 10 and 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
723.918
产品形式:
A solid
纯度:
≥98%
CAS号:
2229711-68-4
分子式:
C45H49N5O4
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