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折扣/货期| 货号：26126-1 mg | 规格：1 mg | 目录价：￥924.6 |
| 货号：26126-10 mg | 规格：10 mg | 目录价：￥7035 |
| 货号：26126-5 mg | 规格：5 mg | 目录价：￥3752 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Asciminib
别名:
ABL001
产品描述:
An allosteric inhibitor of Abl1 (IC50 = 0.45 nM); selective for Abl1 over a panel of more than 60 additional kinases (IC50s = >10 μM), as well as ion channels, nuclear receptors, GPCRs, and transporters; inhibits the proliferation of Luc-Ba/F3 cells transformed with wild-type Bcr-Abl1 or the drug-resistant mutant Bcr-Abl1T315I (GI50s = 1 and 25 nM, respectively), as well as other drug-resistant mutants; reduces tumor growth in a KCL-22 CML mouse xenograft model at 3 mg/kg twice per day and induces tumor regression at ≥7.5 mg/kg twice per day
保存温度:
-20
运输温度:
-20
预期分子量:
449.838326
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
1492952-76-7
分子式:
C20H18ClF2N5O3
促销活动
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