深圳欣博盛生物科技有限公司 a1

ASP3026
货号:18491-1 mg 规格:1 mg 目录价:¥576.2
货号:18491-10 mg 规格:10 mg 目录价:¥2251.2
货号:18491-25 mg 规格:25 mg 目录价:¥4891
货号:18491-5 mg 规格:5 mg 目录价:¥1420.4
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ASP3026
产品描述:
An ALK inhibitor (IC50s = 3.5, 10, and 5.4 nM for the wild-type, ALKF1174L, and ALKR1275Q enzymes, respectively); selective for ALK over a panel of 86 kinases at 1,000 nM but also inhibits ROS1 and TNK2 (IC50s = 8.9 and 5.8 nM, respectively); inhibits the proliferation of Ba/F3 cells expressing NPM-ALK or ELM4-ALK fusion proteins (IC50s = 84 and 56 nM, respectively), as well as several crizotinib-resistant Ba/F3 cells expressing NPM-ALK or ELM4-ALK mutants; induces tumor regression in an NCI H2228 NSCLC mouse xenograft model at 10 and 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
580.7
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1097917-15-1
分子式:
C29H40N8O3S
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