| 货号:28578-1 mg | 规格:1 mg | 目录价:¥1005 |
| 货号:28578-10 mg | 规格:10 mg | 目录价:¥7893 |
| 货号:28578-25 mg | 规格:25 mg | 目录价:¥17232 |
| 货号:28578-5 mg | 规格:5 mg | 目录价:¥4462 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ASP7657
产品描述:
An EP4 antagonist (IC50s = 0.29 and 0.86 nM for the human and rat receptors, respectively); selective for these receptors over rat EP1, EP2, and EP3 receptors (IC50s = >1,000 nM for all), as well as a panel of 42 additional receptors and ion channels (IC50s = >1,000 nM for all); inhibits PGE2-induced increases in cAMP accumulation in Jurkat cells expressing human EP4 and CHO cells expressing the rat receptor (IC50s = 0.29 and 0.86 nM, respectively); inhibits PGE2-induced decreases in LPS-stimulated TNF-α release in isolated rat whole blood; decreases albuminuria in the db/db mouse model of type 2 diabetes at 0.01 and 0.1 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
509.519669
产品形式:
A crystalline solid
纯度:
≥95% (mixture of isomers)
CAS号:
1196045-28-9
分子式:
C28H26F3N3O3
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