深圳欣博盛生物科技有限公司 a1

Atopaxar (hydrobromide)
货号:41395-1 mg 规格:1 mg 目录价:¥670
货号:41395-5 mg 规格:5 mg 目录价:¥2653
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Atopaxar (hydrobromide)
别名:
E5555|ER 172594-06
产品描述:
A PAR1 antagonist (IC50 = 0.019 µM); selectively inhibits thrombin- or TRAP-6 amide-induced aggregation of isolated human platelet-rich plasma (IC50s = 0.064 and 0.09 µM, respectively) over ADP-, PAR4-AP-, U-46619-, or collagen-induced aggregation of isolated human platelet-rich plasma at 10 µM; inhibits IL-6-induced phosphorylation of STAT3 in A549 cells at 10 µM; inhibits transactivation of STAT3 in a reporter assay using A549 cells (IC50 = 5.901 µM); reduces granzyme B- and IL-1β-induced cytotoxicity in iPSC-derived human neurons at 1 µM; increases the time to occlusion of the femoral artery but does not affect bleeding time in a guinea pig model of photochemically induced thrombosis at 30 and 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
527.627643
产品形式:
A solid
纯度:
≥95%
CAS号:
474550-69-1
分子式:
C29H38FN3O5 • HBr
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询