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折扣/货期| 货号：700580 | 规格：96 wells | 目录价：￥7718.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Autotaxin Inhibitor Screening Assay Kit
别名:
ATX Inhibitor Screening Assay Kit
产品描述:
Autotaxin (ATX, Ectonucleotide Pyrophosphatase/Phosphodiesterase-2, ENPP-2, Lysophospholipase D) is a secreted lysophospholipase D that catalyzes the hydrolysis of lysophosphatidylcholine (LPC) to generate lysophosphatidic acid (LPA). LPA is a lipid mediator that activates G protein-coupled receptors and induces a variety of biological responses, such as neurogenesis, angiogenesis, smooth-muscle contraction, platelet aggregation, and wound healing. ATX-LPA signaling is involved in a range of pathologies including tumor progression and inflammation. Cayman’s Autotaxin Inhibitor Screening Assay provides a convenient method for screening human ATX inhibitors. ATX cleaves bis-(p-nitrophenyl) phosphate liberating p-nitrophenol, a yellow product that is measured at 405-415 nm.
保存温度:
-80
运输温度:
-80
有效期:
730
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