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折扣/货期| 货号：17993-1 mg | 规格：1 mg | 目录价：￥657 |
| 货号：17993-10 mg | 规格：10 mg | 目录价：￥5038 |
| 货号：17993-5 mg | 规格：5 mg | 目录价：￥2854 |
| 货号：17993-50 mg | 规格：50 mg | 目录价：￥14110 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AVL-292
别名:
CC-292|Spebrutinib
产品描述:
A covalent BTK inhibitor (IC50 = 5.9 nM); selective for BTK over a panel of 61 kinases when used at 1 µM but does inhibit additional Tec family kinases BMX, Itk, Tec, and TXK (IC50s = 0.7, 36, 6.2, and 8.9 nM, respectively); inhibits naïve human B cell proliferation (EC50 = 3 nM); reduces joint damage, pannus formation, cartilage degradation, and bone erosion in a mouse model of rheumatioid arthritis induced by collagen at 3, 10, and 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
423.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1202757-89-8
分子式:
C22H22FN5O3
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