深圳欣博盛生物科技有限公司 a1

AZD 0156
货号:25648-10 mg 规格:10 mg 目录价:¥2747
货号:25648-25 mg 规格:25 mg 目录价:¥5119
货号:25648-5 mg 规格:5 mg 目录价:¥1729
货号:25648-50 mg 规格:50 mg 目录价:¥8522
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AZD 0156
产品描述:
An inhibitor of ATM kinase (IC50s = 0.04 and 0.57 nM in enzyme and cell-based assays, respectively); selective for ATM over other PIKK family kinases including DNA-PK, mTOR, PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ (IC50s = 0.14, 0.20, 0.32, 1.8, 1.1, and 0.27 μM, respectively, in enzyme assays); enhances the antitumor activity of irinotecan in an SW620 colon cancer mouse xenograft model at 20 mg/kg and olaparib in an HBCx-10 breast cancer PDX mouse model at 5 mg/kg, leading to tumor regression in both models
保存温度:
-20
运输温度:
-20
预期分子量:
461.55624
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1821428-35-6
分子式:
C26H31N5O3
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