深圳欣博盛生物科技有限公司 a1

AZD 3759
货号:19931-1 mg 规格:1 mg 目录价:¥482
货号:19931-10 mg 规格:10 mg 目录价:¥2720
货号:19931-25 mg 规格:25 mg 目录价:¥5065
货号:19931-5 mg 规格:5 mg 目录价:¥1474
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AZD 3759
产品描述:
A brain penetrant inhibitor of EGFR (IC50s = 0.3, 0.2, and 0.2 nM for wild-type, L858R-mutant, and exon 19 deletion-containing EGFRs, respectively); selective for EGFR over 115 other kinases, exhibiting 50s = 7.7 and 7.0 nM, respectively) but has no effect on H838 cells that express wild-type EGFR (GI50 = 21,556 nM); inhibits tumor growth by 78% and induces tumor regression at doses of 7.5 and 15 mg/kg, p.o., respectively in a PC-9 mouse model of NSCLC brain metastasis
保存温度:
-20
运输温度:
-20
预期分子量:
459.9
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1626387-80-1
分子式:
C22H23ClFN5O3
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询