| 货号:37485-1 mg | 规格:1 mg | 目录价:¥590 |
| 货号:37485-10 mg | 规格:10 mg | 目录价:¥4703 |
| 货号:37485-25 mg | 规格:25 mg | 目录价:¥10278 |
| 货号:37485-5 mg | 规格:5 mg | 目录价:¥2653 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AZD 7507
产品描述:
An FMS inhibitor (IC50 = 3 nM); selective for FMS over c-KIT, NUAK1, FLT4, RSK1, and 77 other kinases at 1 µM; induces apoptosis in isolated Fms+ mouse bone marrow cells but not Fms- mouse bone marrow cells at 100 nM; reduces the levels of tumor-associated Fms+ macrophages, increases the number of tumor-associated CD8+ T cells, decreases tumor weight, and increases survival in a UN-KPC-960 murine model of PDAC at 100 mg/kg per day; decreases α-Sma and increases E-cadherin levels on isolated UN-KPC-960 tumors; reduces the levels of Ifn-γ, Il-10, Il-17A, Cxcl2, Ccl2, Ccl7, and Ccl12 in protein lysates from isolated UN-KPC-960 tumors
保存温度:
-20
运输温度:
-20
预期分子量:
454.497523
产品形式:
A solid
纯度:
≥98%
CAS号:
1041852-85-0
分子式:
C23H27FN6O3
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