官网链接
折扣/货期| 货号：16237-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：16237-10 mg | 规格：10 mg | 目录价：￥2050 |
| 货号：16237-5 mg | 规格：5 mg | 目录价：￥1273 |
| 货号：16237-50 mg | 规格：50 mg | 目录价：￥5628 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AZD 9291
别名:
Osimertinib
产品描述:
An inhibitor of mutant EGFRs (IC50s = 1, 12, and 5 nM for EGFRL858R/T790M, EGFRL858R, and EGFRL861Q, respectively); selective for these mutant EGFRs over wild-type EGFR (IC50 = 184 nM), as well as over a panel of approximately 280 other kinases at 1 µM; selectively inhibits the proliferation of NSCLC cells containing activating and/or resistant mutants of EGFR (IC50s = 8-40 nM) over wild-type EGFR-containing Calu-3 and NCI H2073 NSCLC cells (IC50s = 650 and 461 nM, respectively); induces tumor regression in a vandetanib-resistant PC-9 NSCLC mouse xenograft model at doses ranging from 1-10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
499.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1421373-65-0
分子式:
C28H33N7O2
促销活动
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