| 货号:CHI-HF-201B7H5-C050 | 规格:50 ug | 目录价:¥4620 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
B7-H5 [VISTA] (human) (rec.) (His)
别名:
Platelet Receptor Gi24; Dies1; Differentiation of ESC-1; SISP1; C10orf54; VISTA
产品描述:
Platelet receptor Gi24 (also known as Dies1 [Differentiation of ESC-1], SISP1 and C10orf54) is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. On ESCs, Gi24 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state. On tumor cells, Gi24 both promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. This increases the potential for cell motility. Human Gi24 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
宿主来源:
HEK 293 cells
保存温度:
+4°C
运输温度:
BI
预期分子量:
~32kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.01EU/µg protein (LAL test; Lonza).
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