| 货号:R30507 | 规格:100 ug | 目录价:¥6488.05 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BAK Antibody
产品描述:
Bcl2 antagonist killer is a protein that in humans, encoded by the BAK gene. The protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis. The gene spans 7.6 kb and contains 6 exons. By Southern blot analysis of genomic DNA from human/rodent somatic cell hybrids, the gene is localized to chromosome 6. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome. BAK also interacts with the tumor suppressor P53 after exposure to cell stress.
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB, IHC-P, ICC
同种型:
Rabbit IgG
免疫原:
An amino acid sequence from the middle region of human BAK (QVGRQLALIGDDINRRYDSEFQ) was used as the immunogen for this BAK antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Antigen affinity
保存温度:
After reconstitution, the BAK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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