| 货号:11423-1 mg | 规格:1 mg | 目录价:¥844 |
| 货号:11423-10 mg | 规格:10 mg | 目录价:¥4569 |
| 货号:11423-25 mg | 规格:25 mg | 目录价:¥8281 |
| 货号:11423-5 mg | 规格:5 mg | 目录价:¥2492 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BAY 61-3606 (hydrochloride)
产品描述:
A Syk inhibitor (Ki = 7.5 nM); selective for Syk over Lyn, Fyn, Src, Itk, and BTK (Kis = >4.7 µM for all); inhibits anti-IgE-induced histamine release in isolated human mast cells sensitized with IgE (IC50 = 5.1 nM); reduces anti-IgM-induced proliferation of isolated mouse splenic B cells (IC50 = 58 nM); sensitizes MCF-7 human breast cancer cells to TRAIL-induced apoptosis from 0.31-2.5 µM; inhibits passive cutaneous anaphylaxis in rats (ED50 = 8 mg/kg); reduces tumor growth in an MCF-7 mouse xenograft model at 50 mg/kg alone or in combination with TRAIL
保存温度:
-20
运输温度:
-20
预期分子量:
390.44
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1615197-10-8
分子式:
C20H18N6O3 • HCl
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