深圳欣博盛生物科技有限公司 a1

BAY-8400
货号:43707-1 mg 规格:1 mg 目录价:¥1112
货号:43707-10 mg 规格:10 mg 目录价:¥6633
货号:43707-25 mg 规格:25 mg 目录价:¥13829
货号:43707-5 mg 规格:5 mg 目录价:¥4422
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BAY-8400
产品描述:
A DNA-PK inhibitor (IC50 = 0.081 µM); selective for DNA-PK over ATM and mTOR (IC50s = 19.3 and 1.91 µM, respectively) and a panel of 365 additional kinases at 1 µM but does inhibit ATR and PI3Kβ (IC50s = 0.394 and 0.117 µM, respectively); inhibits the formation of γH2AX in ATM-negative HT-144 cells (IC50 = 0.069 nM); reduces the proliferation of HT-29 cells when used alone or in combination with bleomycin; reduces tumor area in an LNCaP prostate cancer mouse xenograft model at 150 mg/kg, p.o. in combination with BAY 2315497
保存温度:
-20
运输温度:
-20
预期分子量:
393.397806
产品形式:
A solid
纯度:
≥98%
CAS号:
2763602-59-9
分子式:
C21H17F2N5O
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