| 货号:17079-1 mg | 规格:1 mg | 目录价:¥1005 |
| 货号:17079-10 mg | 规格:10 mg | 目录价:¥4462 |
| 货号:17079-5 mg | 规格:5 mg | 目录价:¥2492 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BB-Cl-Amidine (trifluoroacetate salt)
产品描述:
A pan PAD inhibitor; irreversibly inhibits PAD1-4 (kinact/KI = 16,100, 4,100, 6,800, and 13,300 M-1min-1, respectively); inhibits PMA-induced NET formation in mouse bone marrow-derived neutrophils at 20 and 200 µM; inhibits HSV-1-induced IFN-β production in mouse BMDMs at 1 µM; reduces diABZI STING agonist-1-induced BMDM IFN-β and TNF-α production in wild-type, Pad2-/-, and Pad4-/- mice at 10 mg/kg; increases survival, as well as reduces splenomegaly, myocarditis, and cardiac fibrosis in a Trex1D18N/D18N mouse model of AGS at 20 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
459.97044
产品形式:
A crystalline solid
纯度:
≥95%
分子式:
C26H26ClN5O • XCF3COOH
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