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折扣/货期| 货号：21945-1 mg | 规格：1 mg | 目录价：￥657 |
| 货号：21945-10 mg | 规格：10 mg | 目录价：￥5668 |
| 货号：21945-5 mg | 规格：5 mg | 目录价：￥2988 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BCI (hydrochloride)
产品描述:
An inhibitor of DUSP6 and DUSP1; a mixture of (E) and (Z) isomers; an (E/Z) isomeric mixture inhibits LPS-induced increases in the production of IL-1β, IL-6, and ROS in RAW 264.7 and isolated mouse peritoneal macrophages in an ERK-independent manner at 0.5-2 µM; an (E/Z) isomeric mixture inhibits proliferation, migration, and invasion of gastric cancer cells in an ERK-dependent manner and reduces tumor growth in a gastric cancer PDX mouse model at 35 mg/kg every seven days; the (E) isomer inhibits DUSP6 and DUSP1 in HeLa cells (IC50s = 12.3 and 11.5 µM, respectively); the (E) isomer induces expansion of the cardiac progenitor cell pool and increases heart size in zebrafish embryos
保存温度:
-20
运输温度:
-20
预期分子量:
317.44
产品形式:
A crystalline solid
纯度:
≥95% (mixture of isomers)
CAS号:
95130-23-7
分子式:
C22H23NO • HCl
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