| 货号:35488-10 mg | 规格:10 mg | 目录价:¥1742 |
| 货号:35488-100 mg | 规格:100 mg | 目录价:¥5494 |
| 货号:35488-5 mg | 规格:5 mg | 目录价:¥925 |
| 货号:35488-50 mg | 规格:50 mg | 目录价:¥3899 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Belotecan (hydrochloride)
别名:
(S)-CKD602|7-[2-(N-isopropylamino)ethyl]-(20S)-Camptothecin|CKD602
产品描述:
A DNA topoisomerase I inhibitor (IC50 = 0.119 µg/ml); a derivative of camptothecin; inhibits the proliferation of KATO III, HT-29, A549, MDA-MB-231, and SKOV3 cells (IC50s = 160, 10.9, 9, 345, and 31 ng/ml, respectively); induces apoptosis and cell cycle arrest at the G2/M phase in, and inhibits invasion of, SiHa cells at 150 ng/ml; reduces tumor growth in a Ca Ski cervical cancer mouse xenograft model at 25 mg/kg; reduces food intake and body weight in pregnant dams and increases fetal deaths and decreases litter size at 80 µg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
433.4997
产品形式:
A solid
纯度:
≥95%
CAS号:
213819-48-8
分子式:
C25H27N3O4 • HCl
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