| 货号:39652-1 mg | 规格:1 mg | 目录价:¥482 |
| 货号:39652-10 mg | 规格:10 mg | 目录价:¥3779 |
| 货号:39652-25 mg | 规格:25 mg | 目录价:¥8254 |
| 货号:39652-5 mg | 规格:5 mg | 目录价:¥2131 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Belzutifan
别名:
MK-6482|PT2977
产品描述:
A HIF-2α inhibitor; inhibits HIF-2α heterodimerization with the ARNT PAS-B domain in a cell-free assay (Ki = 23 nM), activation of HIF-2α in a reporter assay using 786-O renal cell carcinoma cells (IC50 = 17 nM), and secretion of VEGF-A from 786-O cells (EC50 = 17 nM); induces tumor regression in a 786-O mouse xenograft model from 0.3-3 mg/kg; reduces hematocrit levels and right ventricular pressure in mice expressing VHLR200W in a model of Chuvash polycythemia at 0.1 mg/g
保存温度:
-20
运输温度:
-20
预期分子量:
383.342729
产品形式:
A solid
纯度:
≥98%
CAS号:
1672668-24-4
分子式:
C17H12F3NO4S
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