| 货号:39672-1 mg | 规格:1 mg | 目录价:¥1139 |
| 货号:39672-10 mg | 规格:10 mg | 目录价:¥7946 |
| 货号:39672-5 mg | 规格:5 mg | 目录价:¥5119 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BI-749327
产品描述:
A TRPC6 inhibitor (IC50 = 13 nM for the mouse channel); selective for TRPC6 over TRPC3 and TRPC7 (IC50s = 1,100 and 550 nM, respectively, for the mouse channels); inhibits TRPC6-mediated reporter gene expression in HEK293T cells expressing mouse TRPC6 at 100, 250, and 500 nM; decreases myocardial interstitial fibrosis in a mouse model of hypertrophic cardiomyopathy induced by transaortic constriction at 30 mg/kg; reduces unilateral ureteral obstruction-induced renal fibrosis in mice; increases survival, decreases myocardial fibrosis, and improves grip strength in a mouse model of DMD at 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
442.433809
产品形式:
A solid
纯度:
≥98%
CAS号:
2361241-23-6
分子式:
C23H21F3N4O2
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