| 货号:24273-1 mg | 规格:1 mg | 目录价:¥482.4 |
| 货号:24273-10 mg | 规格:10 mg | 目录价:¥3591.2 |
| 货号:24273-25 mg | 规格:25 mg | 目录价:¥7865.8 |
| 货号:24273-5 mg | 规格:5 mg | 目录价:¥2050.2 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BI-882370
产品描述:
A RAF inhibitor (IC50s = 0.8, 0.8, and 0.6 nM for B-RAFV600E, wild-type B-RAF, and C-RAF in the DFG-out inactive conformation, respectively); selective for RAF over a panel of kinases, including LCK, KIT, Src, LYNA, LYNB, and PDGFR (IC50s = 49, 415, 485, 750, 715, and 1,220 nM, respectively); inhibits proliferation of human B-RAF-mutant melanoma cells at 1-10 nM; reduces tumor growth in multiple B-RAF-mutant melanoma and colorectal carcinoma mouse xenograft models at 25 mg/kg twice per day
保存温度:
-20
运输温度:
-20
预期分子量:
569.7
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
1392429-79-6
分子式:
C28H33F2N7O2S
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