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折扣/货期| 货号：11022-10 mg | 规格：10 mg | 目录价：￥522.6 |
| 货号：11022-100 mg | 规格：100 mg | 目录价：￥1822.4 |
| 货号：11022-250 mg | 规格：250 mg | 目录价：￥3886 |
| 货号：11022-50 mg | 规格：50 mg | 目录价：￥1420.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BIBF 1120
别名:
Nintedanib
产品描述:
A VEGFR, FGFR, and PDGFR inhibitor (IC50s = 13-34, 37-610, 59, and 65 nM for VEGFR1-3, FGFR1-4, PDGFRα, and PDGFRβ, respectively); selective for VEGFR, FGFR, and PDGFR over a panel of 33 kinases but does inhibit FLT3, LCK, LYN, and Src (IC50s = 16-156 nM); inhibits growth factor-dependent proliferation of HUVECs, HSMECs, HUASMCs, and BRPs (EC50s = 7-290 nM); reduces tumor microvessel density and the number of PDGFRβ-expressing perivascular cells in a FaDu head and neck small cell carcinoma mouse xenograft model at 100 mg/kg; inhibits tumor growth in a Caki-1 renal cancer mouse xenograft model
保存温度:
-20
运输温度:
-20
预期分子量:
539.6
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
656247-17-5
分子式:
C31H33N5O4
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