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折扣/货期| 货号：22985-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：22985-10 mg | 规格：10 mg | 目录价：￥4181 |
| 货号：22985-25 mg | 规格：25 mg | 目录价：￥9112 |
| 货号：22985-5 mg | 规格：5 mg | 目录价：￥2385 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BLU-285
别名:
Avapritinib
产品描述:
A dual inhibitor of KIT and PDGFRα mutant kinases (IC50s = 0.27 and 0.24 nM for KITD816V and PDGFRαD842V, respectively); >150-fold selective for KITD816V and PDGFRαD842V over a kinase panel at a concentration of 3 μM; has activity against a panel of KIT and PDGFRα loop mutants identified in patients with GISTs (IC50s = D814Y mastocytoma allograft mouse model and a GIST patient-derived mouse xenograft model in a dose-dependent manner when administered at doses ranging from 0.3-30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
498.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1703793-34-3
分子式:
C26H27FN10
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