深圳欣博盛生物科技有限公司 a1

BLU-945
货号:43015-10 mg 规格:10 mg 目录价:¥2104
货号:43015-25 mg 规格:25 mg 目录价:¥3618
货号:43015-5 mg 规格:5 mg 目录价:¥1313
货号:43015-50 mg 规格:50 mg 目录价:¥6566
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BLU-945
别名:
Tigozertinib
产品描述:
An inhibitor of mutant EGFR (IC50s = 0.4 and 0.5 nM for EGFRL858R/T790M and EGFRL858R/T790M/C797S, respectively); selective for these mutants over wild-type EGFR (IC50 = 683 nM) and a panel of >400 kinases at 3 µM; induces tumor regression in a mouse xenograft model using H1975 NSCLC cells, which express EGFRL858R/T790M; inhibits tumor growth in an osimertinib-resistant PDX mouse model of NSCLC using tumors harboring EGFRT790M/C797S with an exon 19 deletion
保存温度:
-20
运输温度:
-20
预期分子量:
556.701403
产品形式:
A solid
纯度:
≥98%
CAS号:
2660250-10-0
分子式:
C28H37FN6O3S
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