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折扣/货期| 货号：22282-10 mg | 规格：10 mg | 目录价：￥1608 |
| 货号：22282-25 mg | 规格：25 mg | 目录价：￥3524 |
| 货号：22282-5 mg | 规格：5 mg | 目录价：￥925 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BMH-21
产品描述:
An RNA polymerase I inhibitor; inhibits expression of the 47S rRNA transcript (IC50 = 60 nM), disrupts the structure of the nucleolus, and leads to removal of the RNA polymerase complex from rDNA by inducing dissociation and destruction of RPA194 through a proteasome-dependent mechanism; activates p53 in the nanomolar range; reduces viability of several cancer cell lines but not of non-cancerous cells (IC50s = 0.7, 1.9, ≥40, and 2.7 µM for A375, human diploid fibroblasts, primary human melanocytes, and HIMEC cells, respectively); inhibits tumor growth in melanoma and colon cancer mouse xenograft models when used at a dose of 25 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
360.4
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
896705-16-1
分子式:
C21H20N4O2
促销活动
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