BMPR1B Antibody-多抗-深圳欣博盛生物科技有限公司

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BMPR1B Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：R31786

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

BMPR1B Antibody

产品描述:

BMPR1B (Bone Morphogenetic Protein Receptor Type IB), also known as ALK6, is a protein which in humans is encoded by the BMPR1B gene. BMPR1B is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. By analysis of a monochromosome hybrid mapping panel and by FISH, Astrom et al. (1999) mapped the BMPR1B gene to chromosome 4q22-q24. Ide et al. (1997) compared BMP receptor expression in normal and cancerous prostate tissues. While BMPR1A and BMPR2 were expressed at similar levels in all prostate tissues, BMPR1B was expressed at a significantly reduced level in cancerous prostate tissue.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB, IHC-P

同种型:

Rabbit IgG

免疫原:

Amino acids 14-184 of human BMPR1B were used as the immunogen for the BMPR1B antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity

保存温度:

After reconstitution, the BMPR1B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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