| 货号:28713 | 规格:1 mg | 目录价:¥5842 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BMS 214662
产品描述:
A potent FTase inhibitor (IC50 = 1.3 nM); selective for FTase over GGTase (IC50 = 1,900 nM); inhibits the growth of MEK2, A2780, and PC3 cancer cells expressing wild-type Ras (IC50s = 2.5, 0.04, and 0.15 μM, respectively), as well as HCT116, MIP, RC-165, and MIA PaCa-2 cells expressing mutant K-Ras (IC50s = 0.06, 0.3, 0.3, and 0.12 μM, respectively); induces apoptosis in HCT116 cells; curative in an HCT116 mouse xenograft model at 600 mg/kg; reduces tumor growth in Calu-1, HT-29, EJ-1, and MIA PaCa-2 mouse xenograft models
保存温度:
-20
运输温度:
-20
预期分子量:
489.61462
产品形式:
A solid
纯度:
≥98%
CAS号:
195987-41-8
分子式:
C25H23N5O2S2
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