深圳欣博盛生物科技有限公司 a1

BMS 470539 (hydrochloride)
货号:22231-1 mg 规格:1 mg 目录价:¥925
货号:22231-10 mg 规格:10 mg 目录价:¥3765
货号:22231-5 mg 规格:5 mg 目录价:¥2265
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BMS 470539 (hydrochloride)
产品描述:
An MC1R agonist; induces cAMP accumulation in B16/F10 murine melanoma cells and in CHO cells overexpressing human MC1R (EC50s = 11.6 and 16.8 nM, respectively); inhibits LPS-induced TNF-α production in mice (ED50 = 10 μmol/kg, s.c.); reduces LPS-induced leukocyte infiltration and paw swelling in mouse models of lung inflammation and delayed-type hypersensitivity, respectively; decreases retinal damage in a mouse model of streptozotocin-induced diabetic retinopathy; increases striatal dopamine levels and decreases the number of striatal α-synuclein aggregates in a mouse model of Parkinson’s disease at 20 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
559.68
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
2341796-82-3
分子式:
C32H41N5O4 • 2HCl
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