深圳欣博盛生物科技有限公司 a1

BMS 690514
货号:44552-1 mg 规格:1 mg 目录价:¥562.8
货号:44552-10 mg 规格:10 mg 目录价:¥3939.6
货号:44552-5 mg 规格:5 mg 目录价:¥2532.6
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BMS 690514
产品描述:
A pan-inhibitor of HER and VEGFR family kinases (IC50s = 5, 19, 60, 50, 50, and 25 nM for EGFR, HER2, HER4, VEGFR1, VEGFR2, and VEGFR3, respectively); selective for these kinases over 11 additional kinases but also inhibits FLT3, CAMKII, LCK, and PKA (IC50s = 110, 170, 220, and 280 nM, respectively); selectively inhibits the proliferation of cancer cells containing EGFR gene amplifications or mutations and HER2 gene amplifications over those expressing wild-type EGFR or not expressing EGFR and HER2; inhibits tumor growth and angiogenesis in an L2987 lung cancer mouse xenograft model at 90 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
368.441
产品形式:
A solid
纯度:
≥98%
CAS号:
859853-30-8
分子式:
C19H24N6O2
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