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折扣/货期| 货号：22049-1 mg | 规格：1 mg | 目录价：￥911 |
| 货号：22049-5 mg | 规格：5 mg | 目录价：￥2265 |
| 货号：22049-500 µg | 规格：500 µg | 目录价：￥482 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BMS 986020
别名:
AM-000152
产品描述:
An LPA1 receptor antagonist (Kb = 0.0067 µM); selective for LPA1 over LPA3 in CHO cells expressing the human receptors (IC50s = 0.3 and >1 µM, respectively); inhibits OATP1B1, OATP1B3, BSEP, MDR3, MRP3, and MRP4 (IC50s = 0.17, 0.57, 4.8, 7.5, 22, and 6.2 µM, respectively); reduces bleomycin-induced lung fibrosis in rats at 30 mg/kg twice per day; decreases total biliary bile acid levels and induces bile duct hyperplasia, cholangitis, and cholestasis in monkeys at 225 and 500 mg/kg per day; decreases infarct volume and neurological deficits in a mouse model of transient MCAO-induced ischemic stroke at 5 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
482.5
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1257213-50-5
分子式:
C29H26N2O5
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