深圳欣博盛生物科技有限公司 a1

BMS 986278
货号:43597-10 mg 规格:10 mg 目录价:¥3886
货号:43597-25 mg 规格:25 mg 目录价:¥7102
货号:43597-5 mg 规格:5 mg 目录价:¥2586
货号:43597-50 mg 规格:50 mg 目录价:¥9045
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BMS 986278
别名:
Admilparant
产品描述:
An antagonist of LPA1 (Kb = 0.0069 µM); selective for LPA1 over a panel of 44 receptors, ion channels, and enzymes when used at concentrations ranging from 30 to 150 µM, including BSEP, MDR3, MRP3, MRP4, OATP1B1, and OATP1B3 (IC50s = >100, >100, 66, 47, 36, and 10 µM, respectively); inhibits LPA-induced histamine release in mice; reduces bleomycin-induced lung fibrosis in rats at 3 and 10 mg/kg, p.o.; unlike BMS 986020, it does not induce bile duct hyperplasia, cholangitis, or cholestasis in cynomolgus monkeys
保存温度:
-20
运输温度:
-20
预期分子量:
445.52
产品形式:
A solid
纯度:
≥98%
CAS号:
2170126-74-4
分子式:
C22H31N5O5
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