| 货号:AG-CP3-0030-M001 | 规格:1 mg | 目录价:¥960 |
| 货号:AG-CP3-0030-M005 | 规格:5 mg | 目录价:¥3840 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Boc-Asp(OMe)-FMK
别名:
Boc-D(OMe)-FMK; Boc-D-FMK; BAF
产品描述:
Cell permeable, irreversible, broad-spectrum caspase inhibitor. Inhibits non-caspase cysteine proteases, as well as cathepsins H and L. Can be used for in vitro and in vivo studies. Contains a methyl ester group, which facilitates uptake by cells and subsequently is removed by cytoplasmic esterases, leaving the functional inhibitor. Inhibits the pro-apoptotic effect of TNF-alpha (IC50=39µM). Shown to reduce the activation of NF-kB, suppresses the phosphorylation of IkBalpha and inhibits TNF-induced expression of ICAM-1 and VCAM-1. Blocks hepatocyte apoptosis in vivo. Neuroprotective.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
263.3
产品形式:
solid
产地:
瑞士
纯度:
>98%
CAS号:
187389-53-3
分子式:
C11H18FNO5
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