深圳欣博盛生物科技有限公司 a1

BP-897
货号:25831-1 mg 规格:1 mg 目录价:¥442
货号:25831-10 mg 规格:10 mg 目录价:¥1956
货号:25831-25 mg 规格:25 mg 目录价:¥3631
货号:25831-5 mg 规格:5 mg 目录价:¥1300
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BP-897
产品描述:
A dopamine D3 receptor partial agonist; selectively binds to the dopamine D3 over the D2, D1, and D4 receptors (Kis = 0.92, 61, 3,000, and 300 nM, respectively, for the recombinant human receptors); selective over α1- and α2-adrenergic receptors (Kis = 60 and 83 nM, respectively) and the serotonin receptor subtypes 5-HT1A and 5-HT7 (Kis = 84 and 345 nM, respectively), as well as muscarinic, histamine, and opioid receptors (Kis = >1 µM for all); increases mitogenesis in NG 108-15 cells with a maximum efficacy of 55%; acts as a dopamine D3 receptor antagonist in a [35S]GTPγS binding assay, inhibiting the effect of dopamine (IC50 = 416.87 nM); reduces cocaine-seeking behavior, but has no reinforcing properties itself, in rats trained to self-administer cocaine at 0.5 and 1 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
417.54336
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
314776-92-6
分子式:
C26H31N3O2 • HCl
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