官网链接
折扣/货期| 货号：79-897 | 规格：0.1 mg | 目录价：￥6598.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BRCA1 (phospho Ser1457) Antibody
别名:
BRCA1, Breast cancer type 1 susceptibility protein, familial breast/ovarian cancer gene 1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
The antibody detects endogenous levels of BRCA1 only when phosphorylated at serine 1457.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
Store antibody at -20˚C for up to one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
产地:
美国
生产商:
Prosci
功能与背景:
The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Plays a central role in DNA repair by facilitating cellular response to DNA repair. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Involved in transcriptional regulation of P21 in response to DNA damage. Required for FANCD2 targeting to sites of DNA damage. May function as a transcriptional regulator. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation
Accession #:
NP_009225.1
您可能感兴趣的产品
Growth Hormone (rat) Polyclonal Antibody for IHC
货号：C03904.25 µl
Goat Anti-ImmunoglobulinG (mouse) Polyclonal Antibody
货号：C03757.10 ml
Goat Anti-ImmunoglobulinG (rat) Polyclonal Antibody
货号：C03756.10 ml
Goat Anti-ImmunoglobulinG (guinea pig) Polyclonal Antibody
货号：C03755.10 ml
Sheep Anti-ImmunoglobulinG (guinea pig) Polyclonal Antibody
货号：C03754.10 ml
Horse Anti-ImmunoglobulinG (rabbit) Polyclonal Antibody
货号：C03753.5 ml
CRF (ovine) Polyclonal Antibody
货号：C03171.500 dtn
Methionine Enkephalin Polyclonal Antibody
货号：C03170.500 dtn
复制QQ号成功，请打开QQ后添加好友进行咨询