| 货号:36183-10 mg | 规格:10 mg | 目录价:¥992 |
| 货号:36183-100 mg | 规格:100 mg | 目录价:¥7839 |
| 货号:36183-50 mg | 规格:50 mg | 目录价:¥4409 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Brequinar (sodium salt)
别名:
DuP-785|NSC 368390
产品描述:
A DHODH inhibitor (IC50 = ~20 nM); selective for DHODH over a panel of greater than 400 kinases at 100 nM; induces differentiation of ER-HoxA9, U937, and THP-1 cells in vitro (EC50s = ~1 µM); induces differentiation of tumor cells and reduces tumor growth in a THP-1 mouse xenograft model at 15 mg/kg three times daily or 5 mg/kg per day; induces differentiation of bone marrow leukemic cells and increases survival In a retroviral transduction mouse model of HoxA9 + Meis1 AML
保存温度:
-20
运输温度:
-20
预期分子量:
374.359606
产品形式:
A solid
纯度:
≥98%
CAS号:
96201-88-6
分子式:
C23H14F2NO2 • Na
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