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折扣/货期| 货号：29454-10 mg | 规格：10 mg | 目录价：￥2251 |
| 货号：29454-25 mg | 规格：25 mg | 目录价：￥4958 |
| 货号：29454-5 mg | 规格：5 mg | 目录价：￥1273 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BRL 44408 (maleate)
产品描述:
An antagonist of α2A-ARs (Ki = 8.56 nM for the recombinant human receptors); >50-fold selective for α2A-ARs over α1-, α2B-, α2C-, β1-, and β2-ARs, as well as 19 other neurotransmitter receptors, transporters, and enzymes in a panel at 1 µM; inhibits forskolin-stimulated cAMP accumulation (IC50 = 92.3 nM in CHO cells expressing the recombinant human α2A-AR); increases norepinephrine and dopamine levels by 200 and 100%, respectively, in rat medial prefrontal cortex at 10 mg/kg; decreases the time rats spend immobile in the forced swim test, indicating antidepressant-like activity at 10 and 30 mg/kg; reduces para-phenylquinone-induced abdominal stretching, indicating analgesic activity, in rats at 10 and 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
215.2943
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
681806-46-2
分子式:
C13H17N3 • C4H4O4
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