BRP [BRINP2-related Peptide]-其他肽-深圳欣博盛生物科技有限公司

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BRP [BRINP2-related Peptide]

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CP3-0048-M005	规格：5 mg	目录价：￥960
货号：AG-CP3-0048-M025	规格：25 mg	目录价：￥3840
货号：AG-CP3-0048-M001	规格：1 mg	目录价：￥360
货号：AG-CP3-0048-M100	规格：100 mg	目录价：￥11520

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

BRP [BRINP2-related Peptide]

别名:

THRILRRLFNLC-NH2

产品描述:

BRP (BRINP2-related peptide) is a 12-amino acid peptide, which was discovered through Peptide Predictor, a computational-functional approach based on prohormone convertase (PCSK) prohormone processing. BRP is generated by the cleavage of the 78-kDa secreted parent protein BRINP2 by enzymes such as PCSK1. The C-terminal amidation of BRP is critical for bioactivity. In mice, humans and pigs, BRINP2 is predominantly expressed in the brain. When administered pharmacologically, BRP reduces food intake and exhibits anti-obesity effects in mice and pigs. BRP administration triggers central FOS activation and acts independently of leptin, GLP-1 receptor (GLP1R) and melanocortin 4 receptor (MC4R). Instead, it activates the central CREB-FOS signaling pathway, specifically by activating some regions of the hypothalamus. BRP does not cause changes in pancreatic activity and does not affect blood glucose levels and insulin secretion. It also does not induce nausea or aversion, unlike GDF15, showing certain advantages in improving metabolism.

宿主来源:

Synthetic.

保存温度:

+4°C

运输温度:

预期分子量:

1540.9 . 60.0

产品形式:

solid

产地:

瑞士

纯度: