深圳欣博盛生物科技有限公司 a1

BYL719
货号:16986-10 mg 规格:10 mg 目录价:¥777
货号:16986-25 mg 规格:25 mg 目录价:¥1394
货号:16986-5 mg 规格:5 mg 目录价:¥429
货号:16986-50 mg 规格:50 mg 目录价:¥1715
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BYL719
别名:
Alpelisib|NVP-BYL719
产品描述:
An inhibitor of PI3Kα (IC50s = 4.6, 4, and 4.8 nM for wild-type, E545K mutant, and H1047R mutant PI3K, respectively); selective for PI3Kα over PI3Kβ, PI3Kδ, PI3Kγ, and PI4Kβ (IC50s = 1,156, 290, 250, and 581 nM, respectively), as well as VPS34, mTOR, DNA-PK, and ATR (IC50s = >9,100 nM for all); reduces tumor volume in a PI3Kα-dependent Rat1-myr-p110α mouse xenograft model at 12.5, 25, and 50 mg/kg; also reduces tumor burden in THP-1 AML and MCF-7 breast cancer mouse xenograft models
保存温度:
-20
运输温度:
-20
预期分子量:
441.5
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1217486-61-7
分子式:
C19H22F3N5O2S
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询