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折扣/货期| 货号：39669-1 mg | 规格：1 mg | 目录价：￥576 |
| 货号：39669-10 mg | 规格：10 mg | 目录价：￥4033 |
| 货号：39669-25 mg | 规格：25 mg | 目录价：￥6472 |
| 货号：39669-5 mg | 规格：5 mg | 目录价：￥2600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
C25-140
产品描述:
An inhibitor of the TRAF6-Ubc13 protein-protein interaction (IC50 = 2.6 µM); selectively inhibits the TRAF6-Ubc13 interaction over the interactions between Ubc13- OTUB1 and Ubc13-Uev1a; selectively inhibits TRAF6-dependent ubiquitination over a panel of various E3 ligase/E2 enzymes, but does inhibit cIAP1 and E1/E2 enzymes in cell-free assays at 30 µM; reduces IL-1β-induced activation of NF-κB in MEFs at 50 µM; topical application reduces scaling and erythema in a mouse model of imiquimod-induced psoriasis; decreases disease severity in a mouse model of collagen-induced arthritis from 6-14 mg/kg twice per day; reduces alveolar septal thickening, pulmonary edema, and inflammatory cell infiltration in BALF in a mouse model of lung injury induced by mechanical ventilation with high tidal volumes
保存温度:
-20
运输温度:
-20
预期分子量:
457.57092
产品形式:
A solid
纯度:
≥98%
CAS号:
1358099-18-9
分子式:
C26H31N7O
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