C4B Antibody / Complement C4B-多抗-深圳欣博盛生物科技有限公司

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C4B Antibody / Complement C4B

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：F40031-0.08ML	规格：0.08 ml	目录价：￥2962.25
货号：F40031-0.4ML	规格：0.4 ml	目录价：￥6343.55

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

C4B Antibody / Complement C4B

产品描述:

This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB, ELISA

同种型:

Rabbit Ig

免疫原:

A portion of amino acids 655-684 from the human protein was used as the immunogen for this C4B antibody.

克隆性:

Polyclonal (rabbit origin)