CASP8 Antibody / Caspase 8 (small subunit)-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

CASP8 Antibody / Caspase 8 (small subunit)

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：R32577

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CASP8 Antibody / Caspase 8 (small subunit)

产品描述:

Caspase 8 is also known as CAP4, MACH or MCH5. The CASP8 gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. In addtion, this protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

WB, IHC-P, FACS

同种型:

Rabbit IgG

免疫原:

Amino acids 410-449 (VSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYE-human) were used as the immunogen for the CASP8 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity

保存温度:

After reconstitution, the CASP8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

您可能感兴趣的产品