官网链接
折扣/货期| 货号：10007955-1 mg | 规格：1 mg | 目录价：￥3216 |
| 货号：10007955-5 mg | 规格：5 mg | 目录价：￥14177.2 |
| 货号：10007955-500 µg | 规格：500 µg | 目录价：￥1795.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CAY10498
别名:
2-phenyl-amino-N6-endo-norbornyladenine
产品描述:
The A1, A2A, A2B, and A3 adenosine receptors (ARs) are ubiquitous G protein-coupled receptors. The four AR subtypes have been implicated in several areas of therapeutic interest such as stroke and other ischemic conditions, as well as inflammation, neurodegenerative diseases, diabetes, and sleep regulation.{13281} A3 AR antagonists are of interest as therapeutic agents in glaucoma agents and inflammation. CAY10498 is a potent and selective A3 AR antagonist exhibiting a Ki of 37 nM with 60 and 200-fold selectivity over A1 and A2A adenosine receptors, respectively.{13281} CAY10498 is also a structural analog of reversine, a dedifferentiation agent of embryonic progenitor cells.{12913} However, no dedifferentiation effects or any connection between A3 AR antagonism and dedifferentiation have been demonstrated.
保存温度:
-20
运输温度:
-20
预期分子量:
320.4
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
863202-33-9
分子式:
C18H20N6
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询