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折扣/货期| 货号：30058-1 mg | 规格：1 mg | 目录价：￥1796 |
| 货号：30058-10 mg | 规格：10 mg | 目录价：￥14177 |
| 货号：30058-5 mg | 规格：5 mg | 目录价：￥8013 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CAY10749
产品描述:
A dual inhibitor of PARP and PI3K (IC50s = 6.03, 3.63, 5.62, and 7.41 nM for PARP1, PARP2, PI3Kα, and PI3Kδ, respectively); selective for these enzymes over PI3Kβ and PI3Kγ (IC50s = 288.4 and 831.76 nM, respectively) and a panel of 374 additional kinases at 1 µM; induces dsDNA break formation in a neutral comet assay and apoptosis in MDA-MB-468 breast cancer cells at 1 µM; inhibits proliferation of eight cancer cell lines (IC50s = 398.11-2,818.38 nM); reduces tumor growth by 73.4% in an MDA-MB-468 mouse xenograft model at 50 mg/kg twice per day
保存温度:
-20
运输温度:
-20
预期分子量:
660.621152
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
2337386-47-5
分子式:
C33H28F4N8O3
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