| 货号:22038-10 mg | 规格:10 mg | 目录价:¥1394 |
| 货号:22038-25 mg | 规格:25 mg | 目录价:¥2841 |
| 货号:22038-5 mg | 规格:5 mg | 目录价:¥871 |
| 货号:22038-50 mg | 规格:50 mg | 目录价:¥3926 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CB-839
别名:
GLS1 Inhibitor III|Telaglenastat
产品描述:
An orally bioavailable noncompetitive inhibitor of GLS1; inhibits GAC (IC50s 50s = 28 and 23 nM, respectively for brain and kidney) compared to GLS2 (IC50 > 1,000 nM for liver); antiproliferative against TNBC cell lines HCC1806 and MDA-MB-231 (IC50s = 49 and 26 nM, respectively), but not against estrogen receptor-positive cells T47D (IC50 > 1,000 nM); inhibits tumor growth by 61% in a patient-derived TNBC xenograft model (200 mg/kg, p.o.); antiproliferative against AML and in synergy with erlotinib against EGFR-driven NSCLC
保存温度:
-20
运输温度:
-20
预期分子量:
571.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1439399-58-2
分子式:
C26H24F3N7O3S
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