深圳欣博盛生物科技有限公司 a1

CC-115
货号:19420-1 mg 规格:1 mg 目录价:¥482
货号:19420-10 mg 规格:10 mg 目录价:¥3591
货号:19420-25 mg 规格:25 mg 目录价:¥7866
货号:19420-5 mg 规格:5 mg 目录价:¥2050
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CC-115
产品描述:
A dual inhibitor of mTOR and DNA-PK (IC50s = 0.021 and 0.013 µM, respectively); selective for mTOR and DNA-PK over PI3Kα, ATM, and ATR (IC50s = 0.85, >30, and >30 µM, respectively); inhibits growth in a panel of 123 cancer cell lines, including breast, head and neck, and lung cancer cells (GI50s = 0.015-1.77 µM); inhibits NHEJ in CAL-51, MDA-MB-231, PC3, and HCT116 cells (IC50s = 3.15, 2.16, 2.72, and 6.35 µM, respectively); reduces tumor growth in a PC3 prostate cancer mouse xenograft model at 0.25, 0.5, and 1 mg/kg twice per day
保存温度:
-20
运输温度:
-20
预期分子量:
336.4
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1228013-15-7
分子式:
C16H16N8O
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