| 货号:21885-1 mg | 规格:1 mg | 目录价:¥871 |
| 货号:21885-5 mg | 规格:5 mg | 目录价:¥2720 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CCR4 Antagonist (hydrochloride)
别名:
C-021
产品描述:
A CCR4 antagonist; inhibits activation of CCR4 by CCL22 in a [35S]GTPγS assay; inhibits chemotaxis in human and mouse CCR4-expressing B300-19 cells (IC50s = 18, 140, and 39 nM, respectively); inhibits microglial activation in the cortex in a mouse model of azoxymethane-induced hepatic encephalopathy at 1 mg/kg per day; reduces azoxymethane-induced increases in Il6 and Il1b expression in mouse cortex; reduces mechanical and thermal sensitivity in a streptozotocin-induced mouse model of type I diabetes at 10-30 µg/animal intrathecally
保存温度:
-20
运输温度:
-20
预期分子量:
467.64694
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1784252-84-1
分子式:
C27H41N5O2 • 2HCl
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