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折扣/货期| 货号：29053-1 mg | 规格：1 mg | 目录价：￥737 |
| 货号：29053-10 mg | 规格：10 mg | 目录价：￥5387 |
| 货号：29053-5 mg | 规格：5 mg | 目录价：￥2881 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CCT129202
产品描述:
An Aurora kinase inhibitor; inhibits Aurora A and B by 82 and 60%, respectively, at 1 μM in cell free assays; selective for Aurora A and B over a panel of 13 kinases at 1 μM; inhibits growth of various cancer cell lines (GI50s = 0.08-1.2 μM); induces DNA accumulation and cell cycle arrest at the G2/M phase, as well as apoptosis in HCT116 cells; increases the accumulation of doxorubicin and rhodamine 123 in MDR KBv200 and MCF-7/adr cells and increases the susceptibility of MDR KBv200, MCF-7/adr, S1-M1-80, and HL60/adr cells to cisplatin and doxorubicin; reduces tumor growth in an HCT116 mouse xenograft model at 100 mg/kg; potentiates the antitumor effects of vincristine in a KBv200 mouse xenograft model
保存温度:
-20
运输温度:
-20
预期分子量:
497.01662
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
942947-93-5
分子式:
C23H25ClN8OS
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