| 货号:25666-1 mg | 规格:1 mg | 目录价:¥1032 |
| 货号:25666-10 mg | 规格:10 mg | 目录价:¥5038 |
| 货号:25666-5 mg | 规格:5 mg | 目录价:¥3055 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CCT244747
产品描述:
A potent Chk1 inhibitor (IC50 = 8 nM); selective for Chk1 over FLT3, Chk2, and CDK1 (IC50s = 600, >10,000, and >10,000 nM, respectively) as well as a panel of 121 additional kinases at 10 μM; reverses cell cycle arrest at the G2/M phase induced by etoposide and SN-38 in HT-29 cells and gemcitabine in SW620 cells; potentiates the genotoxicity of SN-38, gemcitabine, and etoposide in HT-29, SW620, MiaPaCa-2, and Calu-6 cells; in combination with irinotecan or gemcitabine, increases the delay of tumor growth in SW620 and Calu-6 mouse xenograft models, respectively, at 75 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
408.45728
产品形式:
A solid
纯度:
≥98%
CAS号:
1404095-34-6
分子式:
C20H24N8O2
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