| 货号:28775-10 mg | 规格:10 mg | 目录价:¥2211 |
| 货号:28775-5 mg | 规格:5 mg | 目录价:¥1595 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CCT245737
产品描述:
A potent Chk1 inhibitor (IC50 = 1.3 nM); selective for Chk1 over Chk2 (IC50 = 2,440 nM); inhibits etoposide-induced G2 checkpoint arrest in HT-29 colon cancer cells (IC50 = 30 nM); inhibits gemcitabine-induced Chk1 autophosphorylation in an SW620 colon cancer mouse xenograft model at 300 mg/kg; reduces tumor volume when administered alone or in combination with gemcitabine in an HT-29 mouse xenograft model; reduces inguinal, brachial/axillary, and mesenteric lymph node weights in the Eμ-Myc driven transgenic mouse transplant model of lymph gland-infiltrating B cell lymphoma at 150 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
379.340029
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1489389-18-5
分子式:
C16H16F3N7O
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