| 货号:CHI-HR-200CD134-C025 | 规格:25 ug | 目录价:¥4200 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD134 [OX40] (human) (rec.) (His)
别名:
OX40; Tumor Necrosis Factor Receptor Superfamily Member 4; TNFRSF4; ACT35; TXGP1L
产品描述:
CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS antigen and the T cell activation antigen 4-1BB. The human CD134 protein is expressed only on activated CD4+ T blasts, and its ligand has been identified as gp34. Interactions between CD134 and its ligand in vivo are necessary for the differentiation of activated B cells into highly immunoglobulin-producing cells, however not involved in other pathways of antigen-driven differentiation of B cells such as development of memory cells in the germinal centers. In addition, the CD134 and gp34 system directly mediate adhesion of activated T cells to vascular endothelial cells, and contribute to growth stimulation of the virus-infected T cells.
宿主来源:
E. coli
保存温度:
+4°C
运输温度:
BI
产品形式:
solid
存储溶液:
Lyophilized from a concentrated sterile solution containing 50mM Tris-HCl buffer (pH 8.0) and 500mM NaCl.
产地:
瑞士
纯度:
>97% (SDS-PAGE)
内毒素水平:
<0.1EU/µg protein (LAL test; Lonza).
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